Chuang Lab | Decoding Disease at Cellular Resolution

Our Research

At the Chuang Lab, we seek to understand the cellular and molecular mechanisms underlying inflammatory bowel disease (IBD). By integrating human genetics, single-cell and spatial multi-omics, and computational approaches, we investigate how genetic variation shapes cellular behavior, immune responses, and tissue remodeling.

Our research focuses on identifying disease-associated cell states, uncovering mechanisms of chronic inflammation and fibrosis, and translating molecular discoveries into potential biomarkers and therapeutic targets.